17 results for "ITK" in Products
ITK Products
Emtk/Itk/Tsk is a member of the Tec family of Protein Tyrosine Kinase (PTK) expressed in T, NK, and mast cells (1). Structurally, Emtk/Itk/Tsk possesses a tyrosine kinase (TK), a pleckstrin homology (PH) and a TEC homology domain. It also contains both SRC homology 2 (SH2) and a SRC homology 3 (SH3) domains (2). It lacks as well the amino-terminal myristylation signal and the negative autoregulatory phosphorylation site present in all members of the Src family of PTKs (3). Additionally, the Src tyrosine kinase LCK is required for Emtk/Itk/Tsk activation and recruitment by CD28 (4).
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: ITK Antibody [NB100-807]](https://resources.rndsystems.com/images/products/ITK-Antibody-Western-Blot-NB100-807-img0001.jpg "Western Blot: ITK Antibody [NB100-807]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #HL1264 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5G6 |
| Applications: | WB, ELISA, Flow, ICC/IF |
![Western Blot: ITK Antibody (5G6)BSA Free [NBP2-37578]](https://resources.rndsystems.com/images/products/ITK-Antibody-5G6-Western-Blot-NBP2-37578-img0003.jpg "Western Blot: ITK Antibody (5G6)BSA Free [NBP2-37578]")
| Reactivity: | Human |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005546 |
| Applications: | Bioactivity |
Potent ITK inhibitor; also inhibits BTK
| Chemical Name: | (R)-3-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-N-(3-methyl-4-(1-methylethyl))benzamide |
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ITK Antibody [NBP1-31732]](https://resources.rndsystems.com/images/products/ITK-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-31732-img0009.jpg "Immunocytochemistry/ Immunofluorescence: ITK Antibody [NBP1-31732]")
ITK inhibitor
| Chemical Name: | 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![ITK Antibody Western Blot: ITK Antibody [NBP3-24925]](https://resources.rndsystems.com/images/products/nbp3-24925_rabbit-itk-pab-201220231457520.jpg "Western Blot: ITK Antibody [NBP3-24925]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2174 |
| Applications: | IHC, WB, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: ITK Antibody [NBP3-17873]](https://resources.rndsystems.com/images/products/ITK-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-17873-img0001.jpg "Immunocytochemistry/ Immunofluorescence: ITK Antibody [NBP3-17873]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: ITK Overexpression Lysate [NBL1-12080]](https://resources.rndsystems.com/images/products/ITK-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12080-img0002.jpg "Western Blot: ITK Overexpression Lysate [NBL1-12080]")
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #7K2Z9 |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5G12C4 |
| Applications: | WB, ELISA |
![Western Blot: ITK Antibody (5G12C4)BSA Free [NBP1-28893]](https://resources.rndsystems.com/images/products/ITK-Antibody-5G12C4-Western-Blot-NBP1-28893-img0002.jpg "Western Blot: ITK Antibody (5G12C4)BSA Free [NBP1-28893]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #8F10 |
| Applications: | IHC, ELISA |
![Immunohistochemistry: ITK Antibody (8F10) [NBP3-15208]](https://resources.rndsystems.com/images/products/ITK-Antibody-8F10-Immunohistochemistry-NBP3-15208-img0001.jpg "Immunohistochemistry: ITK Antibody (8F10) [NBP3-15208]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Sensitivity: | 0.063 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Sensitivity: | 0.127 ng/mL (example only; lot dependent) |
| Assay Range: | 0.312 - 20 ng/mL (example only; lot dependent) |
| Applications: | ELISA |