4 results for "KCNN3" in Products
KCNN3 Products
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. ...
Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
| Chemical Name: | N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride |
| Purity: | ≥98% |
Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels
| Chemical Name: | 6,7-Dichloro-1H-indole-2,3-dione 3-oxime |
| Purity: | ≥98% |
Negative allosteric modulator of KCa2 (SK) channels
| Chemical Name: | N-[2-[[(1R)-1-[3-(Trifluoromethyl)phenyl]ethyl]amino]-1H-benzimidazol-7-yl]acetamide hydrochloride |
| Purity: | ≥98% |
Potent negative modulator of KCa2.3 and KCa3.1 channels
| Chemical Name: | 1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate) |
| Purity: | ≥98% |