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3 results for "Kv11.1" in Products
Kv11.1 Products
Human ether-a-go-go related gene (HERG) encodes the pore-forming subunit of the delayed rectifier potassium channel IKr. There are two N-terminal splice variants of HERG include the full-length isoform 1 alpha and the shorter isoform 1 beta. Isoform 1 beta lacks the PAS motif and deactivates at a faster rate than isoform 1alpha. Residues within the C-terminal play a role in channel expression and channel gating, including voltage-dependent activation. HERG is expressed in the heart and is ...
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
| Chemical Name: | N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride |
| Purity: | ≥98% |
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KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
| Alternate Names: | Tikosyn,UK 68798 |
| Chemical Name: | 1-(4-Methanesulphonamidophenoxy)-2-[N-(4-methanesulphonamidophenethyl)-N-methylamino]ethane |
| Purity: | ≥98% |
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Kv11.1 (hERG) channel blocker
| Chemical Name: | 1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride |
| Purity: | ≥97% |
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