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KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
KV11.1 (hERG) channel blocker; inhibits rapid delayed rectifier K+ current (IKr)
Calmodulin antagonist. Inhibits myosin light chain kinase
D2-like antagonist; also high affinity 5-HT7 antagonist
KV11.1 (hERG) channel activator; antiarrhythmic
KV11.1 (hERG) and KV4.3 channel activator; antiarrhythmic
Kv11.1 (hERG) channel blocker