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5 results for "LXR beta/NR1H2 Small Molecules and Peptides" in Products
LXR beta/NR1H2 Small Molecules and Peptides
LXR beta is ubiquitously expressed. Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver.
Potent liver X receptor (LXR) agonist; also CAR inverse agonist
| Chemical Name: | N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide |
| Purity: | ≥98% |
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Orally active liver X receptor (LXR) agonist
| Chemical Name: | 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride |
| Purity: | ≥98% |
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Potent LXR antagonist
| Chemical Name: | 2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide |
| Purity: | ≥98% |
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Potent LXR agonist
| Chemical Name: | 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole |
| Purity: | ≥98% |
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Selective LXR inverse agonist
| Chemical Name: | N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]benzenesulfonamide |
| Purity: | ≥98% |
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