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5 results for "Nrf2" in Products
Nrf2 Products
NF-E2 related factor 2 (Nrf2) is a member of the cap 'n collar family of basic leucine zipper transcription factors. By binding antioxidant response elements (AREs), Nrf2 activates the transcription of genes encoding antioxidant and phase II drug-metabolizing enzymes needed to protect cells against oxidative damage. Transcriptional targets regulated by Nrf2 include genes encoding glutathione S-transferases, superoxide dismutase-1, and heme oxygenase-1.
Nrf2 signaling activator
| Chemical Name: | 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole |
| Purity: | ≥98% |
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Nrf2 activator; cell permeable
| Chemical Name: | 2-Methylenebutanedioic acid 4-octyl ester |
| Purity: | ≥98% |
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Nrf2 activator
| Chemical Name: | N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea |
| Purity: | ≥98% |
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Nrf2 activator; inhibits Nrf2/Keap1 interaction
| Chemical Name: | (3S)-1-[4-[[(2,3,5,6-Tetramethylphenyl)sulfonyl]amino]-1-naphthalenyl]-3-pyrrolidinecarboxylic acid |
| Purity: | ≥98% |
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Inhibitor of Keap1- Nrf2 interaction
| Alternate Names: | LH601A |
| Chemical Name: | (1S,2R)-2-[[(1S)-1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3,4-dihydro-2(1H)-isoquinolinyl]carbonyl]cyclohexanecarboxylic acid |
| Purity: | ≥98% |
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