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3 results for "Ryanodine Receptor Inhibitors Small Molecules and Peptides" in Products
Ryanodine Receptor Inhibitors Small Molecules and Peptides
The ryanodine receptors (RyRs) are a family of Ca2+ channels that mediate the release of Ca2+ from intracellular Ca2+ storage organelles. Three RyR isoforms have been identified to date, RyR1, RyR2 and RyR3. The RyRs have a well-established role in the mechanism of excitation-contraction (EC) coupling in striated muscle contraction, and also have a role in secretion and synaptic transmission.
RyRs are expressed in the membrane of the sarcoplasmic (SR)/endoplasmic reticulum and are expressed in ...
Ca2+ release inhibitor
| Chemical Name: | 1H-Pyrrole-2-carboxylic acid, (3S,4R,4aR,6S,7S,8R,8aS,8bR,9S,9aS)-dodecahydro-4,6,7,8a,8b,9a-hexahydroxy-3,6a,9-trimethyl-7-(1-methylethyl)-6,9-methanobenzo[1,2]pentaleno[1,6-bc]furan-8-yl ester |
| Purity: | ≥98% |
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Non-selective CaV2.1 and 2.2 blocker; also blocks TRPV channels
| Chemical Name: | Ammoniated ruthenium oxychloride |
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Ca2+ release inhibitor
| Chemical Name: | 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolinedione sodium salt |
| Purity: | ≥98% |
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