5 results for "S1P3/EDG-3 Small Molecules and Peptides" in Products

S1P3/EDG-3 Small Molecules and Peptides

EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family reg...

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Endogenous agonist at S1P1-5

Chemical Name: (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity: ≥98%
Endogenous agonist at S1P1-5
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S1P1 and S1P3 antagonist

Chemical Name: 2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Purity: ≥95%
S1P1 and S1P3 antagonist
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Potent S1P receptor agonist; also immunosuppressant

Alternate Names: Fingolimod,Gilenya
Chemical Name: 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride
Purity: ≥98%
Potent S1P receptor agonist; also immunosuppressant
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Selective S1P3 receptor allosteric agonist

Chemical Name: N,N-Dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide
Purity: ≥97%
Selective S1P3 receptor allosteric agonist
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S1P3 receptor antagonist

Chemical Name: N-(4-Chlorophenyl)-3,3-dimethyl-2-oxobutanimidic 2-(4-chlorophenyl) hydrazide
Purity: ≥98%
S1P3 receptor antagonist
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