5 results for "S1P4/EDG-6 Small Molecules and Peptides" in Products

S1P4/EDG-6 Small Molecules and Peptides

EDG molecules are G protein-coupled receptors that bind plasma lysophospholipids. The EDG family consists of two subfamilies; the S1P (sphingosine-1-phosphate) subfamily consisting of EDG-1, 3, 5, 6, and 8, and the LPA (lysophosphatidic acid) subfamily that contains EDG-2, 4 and 7. Each receptor is the product of a distinct gene. The S1P family reg...

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Endogenous agonist at S1P1-5

Chemical Name: (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol
Purity: ≥98%
Endogenous agonist at S1P1-5
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Potent and selective S1P4 antagonist

Chemical Name: N-[(4-(Aminomethyl)-2,6-dimethylphenyl]-5-(2,5-dichlorophenyl)-2-furancarboxamide hydrochloride
Purity: ≥97%
Potent and selective S1P4 antagonist
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Potent and selective S1P4 agonist

Chemical Name: 2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine
Purity: ≥98%
Potent and selective S1P4 agonist
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Potent and selective S1P4 agonist

Chemical Name: (2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone
Purity: ≥98%
Potent and selective S1P4 agonist
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S1P1 and S1P3 antagonist

Chemical Name: 2-Amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamaide
Purity: ≥95%
S1P1 and S1P3 antagonist
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