4 results for "SCN11A" in Products

SCN11A Products

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage-gated, type XI, alpha subunit) mediates the voltage-dependent sodium ion permeability and conductance. It forms the pore of the sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform.

Cardiac Na+ channel blocker. Antiarrhythmic

Chemical Name: N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate
Purity: ≥98%
Cardiac Na+ channel blocker. Antiarrhythmic
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Na+ channel blocker; antiarrhythmic agent

Alternate Names: Ko 1173
Chemical Name: 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Purity: ≥98%
Na+ channel blocker; antiarrhythmic agent
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NaV blocker; neuroprotective

Alternate Names: 619C89
Chemical Name: 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine
Purity: ≥98%
NaV blocker; neuroprotective
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Inhibitor of neuronal NaV channels; anticonvulsant

Alternate Names: CBZ
Chemical Name: 5H-Dibenz[b,f]azepine-5-carboxamide
Purity: ≥98%
Inhibitor of neuronal NaV channels; anticonvulsant
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