5 results for "Two-P Potassium Channels Blockers Small Molecules and Peptides" in Products
Two-P Potassium Channels Blockers Small Molecules and Peptides
Two-P potassium channels (K2P) are a family of proteins responsible for background potassium currents, which are important in stabilizing membrane potential. K2Ps are so called because each subunit contains four transmembrane and two pore domains (P loops), although they do not form two pores; it is this 4TM/2P formation that characterizes the members of the K2P channel family. They are thought to form functional dimers within the membrane. Fifteen K2P channels have been identified to date, ...
Potent K2P2.1 (TREK-1) channel blocker
| Purity: | ≥95% |
Potent and selective K2P3.1 (TASK-1) channel blocker
| Chemical Name: | 2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide |
| Purity: | ≥98% |
Potent K2P9.1 (TASK-3) channel blocker
| Chemical Name: | 1-[1-[6-[[1,1'-Biphenyl]-4-ylcarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl]-4-piperidinyl]-1-butanone |
| Purity: | ≥98% |
Potent inhibitor of TREK-1 channels
| Purity: | ≥95% |
Selective and potent inhibitor of both mouse and human THIK-1
| Chemical Name: | 4-[1-(4-Pyridinylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine |
| Purity: | ≥98% |
