CD21 Antibody (CL14556) - BSA Free

Novus Biologicals | Catalog # NBP3-26867

Novus Biologicals

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL14556

Format

BSA Free
View all CD21 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from P20023, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Mouse (81%), Rat (84%)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse CD21 Antibody (CL14556) - BSA Free (NBP3-26867) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CD21 Antibody (CL14556) - BSA Free

CD21 Antibody (CL14556)

Western Blot: CD21 Antibody (CL14556) [NBP3-26867]

Western blot analysis in human cell line Daudi.
CD21 Antibody (CL14556)

Immunohistochemistry-Paraffin: CD21 Antibody (CL14556) [NBP3-26867]

Staining of human lymph node shows strong membranous positivity in germinal center.
CD21 Antibody (CL14556)

Immunohistochemistry-Paraffin: CD21 Antibody (CL14556) [NBP3-26867]

Staining of human tonsil shows strong membranous positivity in germinal center.
CD21 Antibody (CL14556)

Immunohistochemistry-Paraffin: CD21 Antibody (CL14556) [NBP3-26867]

Staining of human skeletal muscle shows no positivity in myocytes as expected.
CD21 Antibody (CL14556)

Immunohistochemistry-Paraffin: CD21 Antibody (CL14556) [NBP3-26867]

Staining of human small intestine shows strong membranous positivity in lymph node.
CD21 Antibody (CL14556)

Immunohistochemistry-Paraffin: CD21 Antibody (CL14556) [NBP3-26867]

Analysis in human tonsil and skeletal muscle tissues. Corresponding RNA-seq data are presented for the same tissues.

Applications for CD21 Antibody (CL14556) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD21

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Alternate Names

C3DR, CD21, CR2

Gene Symbol

CR2

Additional CD21 Products

Product Documents for CD21 Antibody (CL14556) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for CD21 Antibody (CL14556) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for CD21 Antibody (CL14556) - BSA Free

There are currently no reviews for this product. Be the first to review CD21 Antibody (CL14556) - BSA Free and earn rewards!

Have you used CD21 Antibody (CL14556) - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies