Recombinant Human IL-35 Binds IL-12 R beta 2. Recombinant Human IL-12 R beta 2 (Catalog # 1959-B2) was coated onto microplate wells at 5 µg/mL and increasing concentrations of Recombinant Human IL-35 (Catalog # 8608-IL) were added. The concentration of Recombinant Human IL-35 that produces 50% optimal binding response is approximately 20-120 ng/mL.
You've been asking us to provide recombinant IL-35, and now we have it for you. As always, we feel that it is of the utmost importance to take the time needed to ensure that our proteins are the best available. As can be seen in the graph on the right, we've done it again. The enhanced binding of R&D Systems® IL-35 to its receptor IL-12 R beta 2 highlights the specificity of our IL-35 compared to the competition.
Customer Approved "We tested IL-35 from several batches and got expected results. We plan on using your IL-35, and IL-27 as well!" National Heart, Lung and Blood Institute (NHLBI)