6-Biotin-17-NAD

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4670-500-01
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Citations (30)
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6-Biotin-17-NAD Summary

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Preparation and Storage

Stability & Storage
Store the unopened product at -80 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: 6-Biotin-17-NAD

Biotinylated NAD (6-Biotin-17-NAD) provides a non-isotopic alternative to radiolabeled NAD for assays requiring this substrate. For instance, biotinylated NAD can be used as an indirect measure of PARP activity when biotin incorporation is detected using a streptavidin detection system.

Alternate Names
6-Biotin-17-NAD

Citations for 6-Biotin-17-NAD

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

30 Citations: Showing 1 - 10
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  1. Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9
    Authors: CS Yang, K Jividen, A Spencer, N Dworak, L Ni, LT Oostdyk, M Chatterjee, B Ku?mider, B Reon, M Parlak, V Gorbunova, T Abbas, E Jeffery, NE Sherman, BM Paschal
    Mol. Cell, 2017;66(4):503-516.e5.  2017
  2. The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells
    Authors: M Schuster, L Schnell, P Feigl, C Birkhofer, K Mohr, M Roeder, S Carle, S Langer, F Tippel, J Buchner, G Fischer, F Hausch, M Frick, C Schwan, K Aktories, C Schiene-Fi, H Barth
    Sci Rep, 2017;7(1):613.  2017
  3. Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9
    Authors: CS Yang, K Jividen, A Spencer, N Dworak, L Ni, LT Oostdyk, M Chatterjee, B Ku?mider, B Reon, M Parlak, V Gorbunova, T Abbas, E Jeffery, NE Sherman, BM Paschal
    Mol. Cell, 2017;66(4):503-516.e5.  2017
  4. Antitumor activity of a pyrrole-imidazole polyamide.
    Proc Natl Acad Sci U S A, 2013;110(5):1863-8.  2013
  5. The long-lived nature of clostridium perfringens iota toxin in mammalian cells induces delayed apoptosis.
    Authors: Hilger H, Pust S, von Figura G, Kaiser E, Stiles BG, Popoff MR, Barth H
    Infect. Immun., 2009;77(12):5593-601.  2009
  6. The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion.
    Authors: Rodas P, Alamos-Musre A, Alvarez F, Escobar A, Tapia C, Osorio E, Otero C, Calderon I, Fuentes J, Gil F, Paredes-Sabja D, Christodoulides M
    FEMS Microbiol Lett, 0;363(17):.  0
  7. Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.
    Authors: Wei H, Xiang L, Wayne A, Chertov O, Fitzgerald D, Bera T, Pastan I
    Proc Natl Acad Sci U S A, 0;109(18):6898-903.  0
  8. The oligonucleotide/oligosaccharide-binding fold motif is a poly(ADP-ribose)-binding domain that mediates DNA damage response.
    Authors: Zhang F, Chen Y, Li M, Yu X
    Proc Natl Acad Sci U S A, 0;111(20):7278-83.  0
  9. Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment.
    Authors: Zhou M, Ottenberg G, Sferrazza G, Hubbs C, Fallahi M, Rumbaugh G, Brantley A, Lasmezas C
    Brain, 0;138(0):992-1008.  0
  10. Tankyrase-mediated beta-catenin activity regulates vasopressin-induced AQP2 expression in kidney collecting duct mpkCCDc14 cells.
    Authors: Jung H, Kim S, Choi H, Park E, Lim J, Frokiaer J, Nielsen S, Kwon T
    Am J Physiol Renal Physiol, 0;308(5):F473-86.  0
  11. Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.
    Authors: Khadka P, Hsu J, Veith S, Tadokoro T, Shamanna R, Mangerich A, Croteau D, Bohr V
    Mol Cell Biol, 0;35(23):3974-89.  0
  12. Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair.
    Authors: Robu M, Shah R, Petitclerc N, Brind'Amour J, Kandan-Kulangara F, Shah G
    Proc Natl Acad Sci U S A, 0;110(5):1658-63.  0
  13. Thermal Unfolding of the Pertussis Toxin S1 Subunit Facilitates Toxin Translocation to the Cytosol by the Mechanism of Endoplasmic Reticulum-Associated Degradation.
    Authors: Banerjee T, Cilenti L, Taylor M, Showman A, Tatulian S, Teter K
    Infect Immun, 0;84(12):3388-3398.  0
  14. Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion.
    Authors: Simon N, Barbieri J
    J Biol Chem, 0;289(15):10650-9.  0
  15. NAD-dependent ADP-ribosylation of the human antimicrobial and immune-modulatory peptide LL-37 by ADP-ribosyltransferase-1.
    Authors: Picchianti M, Russo C, Castagnini M, Biagini M, Soldaini E, Balducci E
    Innate Immun, 0;21(3):314-21.  0
  16. CTCF participates in DNA damage response via poly(ADP-ribosyl)ation.
    Authors: Han D, Chen Q, Shi J, Zhang F, Yu X
    Sci Rep, 0;7(0):43530.  0
  17. The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response.
    Authors: Zhang F, Shi J, Chen S, Bian C, Yu X
    Nucleic Acids Res, 0;43(22):10782-94.  0
  18. Crystal structure of human ADP-ribose transferase ARTD15/PARP16 reveals a novel putative regulatory domain.
    Authors: Karlberg T, Thorsell A, Kallas A, Schuler H
    J Biol Chem, 0;287(29):24077-81.  0
  19. Wide Variability in the Time Required for Immunotoxins to Kill B Lineage Acute Lymphoblastic Leukemia Cells: Implications for Trial Design.
    Authors: Muller F, Cunningham T, Liu X, Wayne A, Pastan I
    Clin Cancer Res, 0;22(19):4913-4922.  0
  20. Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development.
    Authors: Liu S, Bachran C, Gupta P, Miller-Randolph S, Wang H, Crown D, Zhang Y, Wein A, Singh R, Fattah R, Leppla S
    Proc Natl Acad Sci U S A, 0;109(34):13817-22.  0
  21. BEC, a novel enterotoxin of Clostridium perfringens found in human clinical isolates from acute gastroenteritis outbreaks.
    Authors: Yonogi S, Matsuda S, Kawai T, Yoda T, Harada T, Kumeda Y, Gotoh K, Hiyoshi H, Nakamura S, Kodama T, Iida T
    Infect Immun, 0;82(6):2390-9.  0
  22. Structural basis for lack of ADP-ribosyltransferase activity in poly(ADP-ribose) polymerase-13/zinc finger antiviral protein.
    Authors: Karlberg T, Klepsch M, Thorsell A, Andersson C, Linusson A, Schuler H
    J Biol Chem, 0;290(12):7336-44.  0
  23. Identification of PARP14 inhibitors using novel methods for detecting auto-ribosylation.
    Authors: Yoneyama-Hirozane M, Matsumoto S, Toyoda Y, Saikatendu K, Zama Y, Yonemori K, Oonishi M, Ishii T, Kawamoto T
    Biochem Biophys Res Commun, 0;486(3):626-631.  0
  24. Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage.
    Authors: Steffen J, McCauley M, Pascal J
    Nucleic Acids Res, 0;44(20):9771-9783.  0
  25. The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.
    Authors: Oplustil O'Connor L, Rulten S, Cranston A, Odedra R, Brown H, Jaspers J, Jones L, Knights C, Evers B, Ting A, Bradbury R, Pajic M, Rottenberg S, Jonkers J, Rudge D, Martin N, Caldecott K, Lau A, O'Connor M
    Cancer Res, 0;76(20):6084-6094.  0
  26. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.
    Authors: Hu Y, Petit S, Ficarro S, Toomire K, Xie A, Lim E, Cao S, Park E, Eck M, Scully R, Brown M, Marto J, Livingston D
    Cancer Discov, 0;4(12):1430-47.  0
  27. Homogeneous screening assay for human tankyrase.
    Authors: Narwal M, Fallarero A, Vuorela P, Lehtio L
    J Biomol Screen, 0;17(5):593-604.  0
  28. Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth.
    Authors: Li N, Zhang Y, Han X, Liang K, Wang J, Feng L, Wang W, Songyang Z, Lin C, Yang L, Yu Y, Chen J
    Genes Dev, 0;29(2):157-70.  0
  29. Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.
    Authors: King B, Cooper K, Liu K, Hudson L
    J Biol Chem, 0;287(47):39824-33.  0
  30. Protein Kinase Inhibitor H89 Enhances the Activity of Pseudomonas Exotoxin A-Based Immunotoxins.
    Authors: Liu X, Muller F, Wayne A, Pastan I
    Mol Cancer Ther, 0;15(5):1053-62.  0

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