8-(3-Chlorostyryl)caffeine

Catalog # Availability Size / Price Qty
3306/10
3306/50
Cat.No. 3306 - 8-(3-Chlorostyryl)caffeine | C16H15ClN4O2 | CAS No. 147700-11-6
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Description: Selective A2A antagonist. Also MAO-B inhibitor
Alternative Names: CSC

Chemical Name: (E)-8-[2-(3-Chlorophenyl)ethenyl]-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Purity: ≥99%

Product Details
Citations (4)
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Biological Activity

Selective adenosine A2A receptor antagonist and monoamine oxidase B (MAO-B) inhibitor (Ki values are 54 and 28200 nM at rat A2A and A1 receptors respectively and Ki ~ 100 nM at MAO-B). Potently protects against quinolinic acid-induced (Cat. No. 0225) neuronal damage and is neuroprotective in the MPTP model of Parkinson's disease.

Technical Data

M.Wt:
330.77
Formula:
C16H15ClN4O2
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
147700-11-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for 8-(3-Chlorostyryl)caffeine

The citations listed below are publications that use Tocris products. Selected citations for 8-(3-Chlorostyryl)caffeine include:

4 Citations: Showing 1 - 4

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