Selective antagonist of α
4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including α
4 and α
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α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release.
Luo et al.
Relating neuronal nicotinic acetylcholine receptor subtypes defined by subunit composition and channel function.
Nai et al.
An α3β4 subunit combination acts as a major functional nicotinic acetylcholine receptor in male rat pelvic ganglion neurons.
Park et al.
Pflugers Arch., 2006;452:775