Selective antagonist of α
6-containing nicotinic receptors that discriminates between the closely related α
6 and α
3 subunits (IC50
values are 0.95 and 74.2 nM for rat α
3 and α
2 receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under license from University of Utah
α-Conotoxin PIA is selective for α6 subunit-containing nicotinic acetylcholine receptors.
Dowell et al.
Effect of novel α-Conotoxins on nicotine-stimulated [3H]Dopamine release from rat striatal synaptosomes.
Azam and McIntosh
Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors.
Chi et al.