Chemical Name: 1H-Benzotriazol-1-amine
Biological ActivityABT is a cytochrome P450 inhibitor. Inhibits synthesis of the eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE). Reduces intimal hyperplasia and vascular remodeling following endothelial injury in rat carotid arteries.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.
Mathews et al.
20-hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.
Orozco et al.
Citation for ABT
The citations listed below are publications that use Tocris products. Selected citations for ABT include:
1 Citation: Showing 1 - 1
Further evidence for the role of IP 3R 1 in regulating subsynaptic gene expression and neuromuscular transmission.
Authors: Zhu and Gomez
Pharmacol Res Perspect 2012;6:65
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