ABT
Chemical Name: 1H-Benzotriazol-1-amine
Purity: ≥98%
Biological Activity
Cytochrome P450 inhibitor. Inhibits synthesis of the eicosanoid 20-hydroxyeicosatetraenoic acid (20-HETE). Reduces intimal hyperplasia and vascular remodeling following endothelial injury in rat carotid arteries.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Inactivation of rabbit pulmonary cytochrome P-450 in microsomes and isolated perfused lungs by the suicide substrate 1-aminobenzotriazole.
Mathews et al.
J.Pharmacol.Exp.Ther., 1985;235:186 -
20-hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries.
Orozco et al.
J.Pharmacol.Exp.Ther., 2013;346:67
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for ABT
The citations listed below are publications that use Tocris products. Selected citations for ABT include:
1 Citation: Showing 1 - 1
-
Further evidence for the role of IP 3R 1 in regulating subsynaptic gene expression and neuromuscular transmission.
Authors: Zhu and Gomez
Pharmacol Res Perspect 2012;6:65
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for ABT
There are currently no reviews for this product. Be the first to review ABT and earn rewards!
Have you used ABT?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image