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Ac-IEPD-AFC

Catalog #: 1576 Datasheet / COA / SDS

Discontinued Product

1576 has been discontinued.
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Ac-IEPD-AFC
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Description: Fluorogenic granzyme B substrate

Chemical Name: N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin)

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Biological Activity

Peptide sequence shown to be preferred recognition motif for the serine protease granzyme B. Fluorogenic substrate.

Technical Data

M.Wt:
725.67
Formula:
C32H38F3N5O11
Sequence:
IEPD

(Modifications: Ile-1 = N-Ac-Ile, Asp-4 = Asp-(7-amino-4-trifluoromethylcoumarin))

Solubility:
Soluble to 14.51 mg/ml in DMSO
Storage:
Desiccate at -20°C
CAS No:
1135417-31-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A combinatorial approach defines specificities of members of the caspase family and granzyme B.
    Thornberry et al.
    J.Biol.Chem., 1997;272:17907

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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