Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC.
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Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells.
Ito et al.
Mechanism of nitric oxide-induced apoptosis in human neuroblastoma SH-SY5Y cells.
Moriya et al.
FEBS Lett., 2000;484:253