ACDPP hydrochloride

Catalog # Availability Size / Price Qty
2254/10
2254/50
ACDPP hydrochloride | Group I mGluR Antagonists
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Description: Selective mGlu5 antagonist

Chemical Name: 3-Amino-6-chloro-5-dimethylamino-N-2-pyridinylpyrazinecarboxamide hydrochloride

Purity: ≥99%

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Biological Activity

Antagonist at the mGlu5 receptor (Ki = 295 nM). Inhibits human mGlu5 receptor-mediated calcium flux with an IC50 of 134 nM.

Technical Data

M.Wt:
329.19
Formula:
C12H13ClN6O.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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