α-Conotoxin MII

Catalog # Availability Size / Price Qty
1340/500U
α-Conotoxin MII
1 Image
Description: Potent and selective α3β2 and β3 nAChR antagonist

Purity: ≥95%

Product Details
Citations (1)
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Biological Activity

α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes). Also potently blocks β3-containing neuronal nicotinic receptors. Displays > 200-fold selectivity for α3β2 over α2β2, α4β2 and α3β4.

Technical Data

M.Wt:
1710.99
Formula:
C67H103N23O22S4
Sequence:
GCCSNPVCHLEHSNLC

(Modifications: Disulfide bridges: 2-8, 3-16, Cys-16 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
175735-93-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from the University of Utah.

Product Datasheets

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Citation for α-Conotoxin MII

The citations listed below are publications that use Tocris products. Selected citations for α-Conotoxin MII include:

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