α-Estradiol

Key Product Details

Product Description

α

-Estradiol is an endogenous estrogen receptor ligand (K_i values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).

β-Estradiol also available.

Product Specifications for α-Estradiol

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for α-Estradiol

The following data is based on the product molecular weight 272.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.67 mL	18.36 mL	36.71 mL
5 mM	0.73 mL	3.67 mL	7.34 mL
10 mM	0.37 mL	1.84 mL	3.67 mL
50 mM	0.07 mL	0.37 mL	0.73 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Toran-Allerand ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J.Neurosci. 2002 PMID: 12351713
• Kuiper Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 1997 PMID: 9048584

Product Documents for α-Estradiol