Catalog Number: 2823
Chemical Name: (17α)-Estra-1,3,5(10)-triene-3,17-diol
Biological Activity
Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).

β-Estradiol also available.

Technical Data
  • M.Wt:
    272.38
  • Formula:
    C18H24O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >96%
  • Storage:
    Store at RT
  • CAS No:
    57-91-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β.
    Kuiper et al.
    Endocrinology, 1997;138:863
  2. ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury.
    Toran-Allerand et al.
    J.Neurosci., 2002;22:8391
Citations:

The citations listed below are publications that use Tocris products. Selected citations for α-Estradiol include:

3 Citations: Showing 1 - 3
Filter your results:

  1. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system.
    Authors: Tozzi Et al.
    Front Cell Neurosci 2015;9:192
  2. Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae.
    Authors: Dexter Et al.
    Sci Rep 2015;9:17
  3. Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway.
    Authors: McIsaac Et al.
    Mol Biol Cell 2012;23:2993

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