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α-Spinasterol

Catalog #: 4729 Datasheet / COA / SDS

Discontinued Product

4729 has been discontinued.
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α-Spinasterol | CAS No. 481-18-5 | TRPV Antagonists
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Description: TRPV1 antagonist; active in vivo

Chemical Name: (3β,5α,22E)-Stigmasta-7.22-dien-3-ol

Purity: ≥95%

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Biological Activity

α-Spinasterol is a TRPV1 antagonist (IC50 = 1.4 μM). Reduces capsaicin-mediated Ca2+ influx in vitro; displays antinociceptive and antiedematogenic effects in multiple mouse models of pain. Brain penetrant and orally bioavailable.

Technical Data

M.Wt:
412.69
Formula:
C29H48O
Solubility:
Soluble to 10 mM in ethanol with gentle warming
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
481-18-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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