α-Spinasterol

Catalog # Availability Size / Price Qty
4729/1
Cat.No. 4729 - alpha-Spinasterol | C29H48O | CAS No. 481-18-5
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Description: TRPV1 antagonist; active in vivo

Chemical Name: (3β,5α,22E)-Stigmasta-7.22-dien-3-ol

Purity: ≥95%

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Biological Activity

TRPV1 antagonist (IC50 = 1.4 μM). Reduces capsaicin-mediated Ca2+ influx in vitro; displays antinociceptive and antiedematogenic effects in multiple mouse models of pain. Brain penetrant and orally bioavailable.

Technical Data

M.Wt:
412.69
Formula:
C29H48O
Solubility:
Soluble to 10 mM in ethanol with gentle warming
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
481-18-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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