Alphaxalone

   
Product Datasheet
Catalog Number:3046
Chemical Name:(3α,5α)-3-Hydroxypregnane-11,20-dione
Product Details
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Biological Activity
A neurosteroid anesthetic that directly activates and potentiates GABAA receptor-activated membrane current (IGABA). Efficacy but not potency is determined by the alpha subunit of the receptor (EC50 values are 1.4, 1.8, 2.1, 2.4 and 2.5 μM for α1β1γ3, α1β1γ1, β1γ1, α2β1γ2L and α1β1γ2L isoforms respectively).
Technical Data
  • M.Wt:
    332.48
  • Formula:
    C21H32O3
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    23930-19-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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