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AM-TS23

Catalog #: 5211 Datasheet / COA / SDS

Discontinued Product

5211 has been discontinued.
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AM-TS23 | CAS No. 1489285-17-7 | RNA/DNA Polymerase Inhibitors
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Description: DNA polymerase λ and β inhibitor

Chemical Name: (5Z)-5-[[(4-[(2-Methylphenyl)thio]-3-nitrophenyl]methylene]-2-thioxo-4-thiazolidinone

Purity: ≥98%

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Biological Activity

DNA polymerase λ and β inhibitor (IC50 values are 3.9 and 18.2 μM, respectively). Sensitizes human colorectal cancer cells to hydrogen peroxide and temozolomide (Cat. No. 2706) in vitro.

Technical Data

M.Wt:
388.48
Formula:
C17H12N2O3S3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1489285-17-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Expanding the scope of human DNA polymerase λ and β inhibitors.
    Strittmatter et al.
    ACS Chem.Biol., 2014;9:282

Product Datasheets

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