Amyloid β-Peptide (10-20) (human)
Description: Amyloid β-peptide; substrate for MMP-2
Alternative Names: β-AP (10-20)
Biological Activity
Soluble amyloid β-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.Technical Data
M.Wt:
1446.67
Formula:
C71H99N17O16
Sequence:
YEVHHQKLVFF
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
152286-31-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.
Miyazaki et al.
Nature, 1993;362:839 -
Proteolysis of Aβ peptide from Alzheimer disease brain by gelatinase A.
Roher et al.
Biochem.Biophys.Res.Commun., 1994;205:1755
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