Anti- Teprotumumab (Anti-Idiotype) Antibody Summary
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Teprotumumab by Western Blot. Western blot shows Centuximab, Brentuximab, Teprotumumab, Aducanumab, and Ipilimumab. PVDF membrane was probed with 1 µg/mL of Rabbit Anti-Anti- Teprotumumab (Anti-Idiotype) Monoclonal Antibody (Catalog # MAB96342) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # HAF008). A specific band was detected for Teprotumumab at approximately 240 kDa (as indicated). Human IgG is shown as a loading control. This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
The anti-Teprotumumab antibody is an anti-Idiotype antibody raised against and selected for the antigenic determinants of the variable region of Teprotumumab. The antibody has been tested against a broad range of other biosimilars to ensure specificity. This highly specialized anti-idiotypic antibody can be used in a variety of pharmacokinetic (PK) assay formats.
What is an anti-idiotype antibody?
An anti-idiotype antibody is specific for the unique variable (antigen binding) region of another antibody. We have anti-idiotype antibodies to commecially available therapeutic antibodies or biosimilars.
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