Apolipoprotein A5 Antibody (4H8H8E2) [Alexa Fluor™ Plus 647]

Novus Biologicals | Catalog # NB110-57307AFP647

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Alexa Fluor Plus 647

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 4H8H8E2
View all Apolipoprotein A5 Primary Antibodies »

Product Specifications

Immunogen

Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E. Coli strain BL21 (DE3). [UniProt# Q6Q788]

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Apolipoprotein A5 Antibody (4H8H8E2) [Alexa Fluor™ Plus 647]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

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Spectra Viewer
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Apolipoprotein A5

Apolipoprotein A5 (ApoA5) is a minor apolipoprotein, predominantly associated with HDL and and occasionally with VLDL and chylomicrons. ApoA-5 is a useful indicator of plasma triglyceride levels, a major risk factor for coronary artery disease.

Apo A5 is expressed in the plasma and the liver, where it is involved in the early phase of liver regeneration.

APOA5 mutations can lead to increaased susceptibility to familial hypertriglyceridemia (FHTR), a common inherited disorder where VLDL concentrations are elevated in the plasma. This disorder increases the risk of heart disease, obesity, and pancreatitis. APOA5 mutations can also cause hyperlipoproteinemia type 5 (HLPP5), characterized by increased amounts of chylomicrons/VLDL and decreased amounts of LDL/HDL in the plasma. This disorder often leads to a wide array of syndromes, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A

ApoA5 antibodies are useful for studying lipoprotein processing and a variety of cardiac diseases.

Alternate Names

APOAV, apo-AV, APOA-V, Apolipoprotein A5, apolipoprotein A-V, FLJ97995, MGC126836, RAP3MGC126838, Regeneration-associated protein 3

Gene Symbol

APOA5

Additional Apolipoprotein A5 Products

Product Documents for Apolipoprotein A5 Antibody (4H8H8E2) [Alexa Fluor™ Plus 647]

Certificate of Analysis

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Product Specific Notices for Apolipoprotein A5 Antibody (4H8H8E2) [Alexa Fluor™ Plus 647]



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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