AR-M 1000390 hydrochloride
Chemical Name: N,N-Diethyl-4-(phenyl-4-piperidinylidenemethyl)-benzamide hydrochloride
Biological ActivityNon-peptidic, low-internalizing δ-selective opioid receptor agonist; derivative of SNC 80 (Cat. No. 0764). Does not trigger acute desensitization of the analgesic response; reduces CFA-induced hyperalgesia. Brain penetrant following systemic administration.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological characterization of AR-M1000390 at human opioid delta receptors.
Marie et al.
Life Sci., 2003;73:1691
Ligand-directed trafficking of the δ-opioid receptor in vivo: Two paths toward analgesic tolerance.
Pradhan et al.
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