Catalog Number: 2756
Chemical Name: 5Z,8Z,11Z,14Z-Eicosatetraenoic acid
Biological Activity
Endogenous free fatty acid released from phospholipids by phospholipase A2, in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.

Tocrisolve Control also available.

Technical Data
  • M.Wt:
    304.47
  • Formula:
    C20H32O2
  • Storage:
    Store at +4°C
  • CAS No:
    506-32-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Roles of cPLA and arachidonic acid in cancer.
    Nakanishi et al.
    Biochim.Biophys.Acta, 2006;1761:1335
  2. Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation.
    Levick et al.
    J.Immunol., 2007;178:641
  3. Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12-lipoxygenase activation in glioma cells.
    Higuchi et al.
    Life Sci., 2007;80:1856

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