Endogenous free fatty acid released from phospholipids by phospholipase A2
, in water-soluble emulsion (for details see TocrisolveTM 100
, Cat. No. 1684). Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Roles of cPLA2α and arachidonic acid in cancer.
Nakanishi et al.
Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation.
Levick et al.
Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12-lipoxygenase activation in glioma cells.
Higuchi et al.
Life Sci., 2007;80:1856