Tocrisolve™ 100

  ( 22 citations )    
Product Datasheet
Catalog Number:1684
Chemical Name:
Product Details
Citations (22)
Biological Activity
Water soluble emulsion composed of a 1:4 ratio of soya oil/water that is emulsified with the block co-polymer Pluronic F68. Can be diluted with any aqueous medium. Used to solubilize hydrophobic organic chemicals and water-insoluble lipids such as cannabinoids and vanilloids. The cannabinoid or vanilloid is incorporated with the emulsion as part of a specialized innovative production process. The soya oil forms a coating around the cannabinoid molecule, and the block co-polymer is added to stabilize the emulsion, preventing the lipid droplets from coalescing (merging) in the surrounding water. Also can be used as a negative control for reagents in TocrisolveTM 100; Anandamide, AM 404, VDM 11, ACPA, (R)-(+)-Methanandamide, JWH 133 and Arachidonic acid (Cat. Nos. 1017, 1685, 1686, 1781, 1782, 1783 and 2756 respectively).

Tocrisolve™ 100 Technical Support.

Technical Data
  • Storage:
    Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Product Datasheets

The citations listed below are publications that use Tocris products. Selected citations for Tocrisolve™ 100 include:

22 Citations: Showing 1 - 10
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  1. Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury.
    Authors: Hwang Et al.
    J Neuroinflammation  2015;38:843
  2. Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra.
    Authors: Nishikawa Et al.
    Br J Pharmacol  2015;10:e0135701
  3. Anti-inflammatory effects of cannabinoid CB(2) receptor activation in endotoxin-induced uveitis.
    Authors: Toguri Et al.
    Behav Brain Res  2014;171:1448
  4. Cannabinoid receptor type-2 stimulation, blockade, and deletion alters the vascular inflammatory responses to traumatic brain injury.
    Authors: Amenta Et al.
    PLoS One  2014;11:191
  5. Inhibition of p38/Mk2 signaling pathway improves the anti-inflammatory effect of WIN55 on mouse experimental colitis.
    Authors: Li Et al.
    Lab Invest  2013;93:322
  6. Rapid Glucocorticoid-Induced Activation of TRP and CB1 Receptors Causes Biphasic Modulation of Glutamate Release in Gastric-Related Hypothalamic Preautonomic Neurons.
    Authors: Boychuk Et al.
    Front Neurosci  2013;7:3
  7. Electroacupuncture modulation of reflex hypertension in rats: role of cholecystokinin octapeptide.
    Authors: Li Et al.
    Am J Physiol Regul Integr Comp Physiol  2013;305:R404
  8. Treatment with CB2 agonist JWH-133 reduces histological features associated with erectile dysfunction in hypercholesterolemic mice.
    Authors: Fraga-Silva Et al.
    Clin Dev Immunol  2013;2013:263846
  9. Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice.
    Authors: Redondo Et al.
    ACS Chem Neurosci  2012;3:793
  10. The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.
    Authors: Montecucco Et al.
    Br J Pharmacol  2012;33:846
  11. Inhibition of GSK3 attenuates amphetamine-induced hyperactivity and sensitization in the mouse.
    Authors: Enman and Unterwald
    J Neurosci  2012;231:217
  12. Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.
    Authors: Hilgers Et al.
    J Pharmacol Exp Ther  2010;333:210
  13. Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization.
    Authors: Zhang Et al.
    Eur J Neurosci  2010;31:225
  14. Selective reduction of cholecystokinin-positive basket cell innervation in a model of temporal lobe epilepsy.
    Authors: Wyeth Et al.
    J Neurosci  2010;30:8993
  15. Allosteric block of KCa2 channels by apamin.
    Authors: Lamy Et al.
    J Biol Chem  2010;285:27067
  16. Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex.
    Authors: Ho Et al.
    Br J Pharmacol  2010;160:736
  17. Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices.
    Authors: Mendiguren and Pineda
    Br J Pharmacol  2009;158:1579
  18. Differential endocannabinoid regulation of baroreflex-evoked sympathoinhibition in normotensive versus hypertensive rats.
    Authors: Brozoski Et al.
    Auton Neurosci  2009;150:82
  19. Processing cardiovascular information in the vlPAG during electroacupuncture in rats: roles of endocannabinoids and GABA.
    Authors: Tjen-A-Looi Et al.
    J Appl Physiol (1985)  2009;106:1793
  20. Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons.
    Authors: Akerman Et al.
    J Pharmacol Exp Ther  2007;320:64
  21. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression.
    Authors: Esposito Et al.
    Br J Pharmacol  2007;151:1272
  22. Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats.
    Authors: Gaskari Et al.
    Eur Heart J  2005;146:315
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