Water soluble emulsion composed of a 1:4 ratio of soya oil/water that is emulsified with the block co-polymer Pluronic F68. Can be diluted with any aqueous medium. Used to solubilize hydrophobic organic chemicals and water-insoluble lipids such as cannabinoids and vanilloids. The cannabinoid or vanilloid is incorporated with the emulsion as part of a specialized innovative production process. The soya oil forms a coating around the cannabinoid molecule, and the block co-polymer is added to stabilize the emulsion, preventing the lipid droplets from coalescing (merging) in the surrounding water. Also can be used as a negative control for reagents in TocrisolveTM
, AM 404
, VDM 11
, JWH 133
and Arachidonic acid
(Cat. Nos. 1017, 1685, 1686, 1781, 1782, 1783 and 2756 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Chronic topical administration of WIN-55-212-2 maintains a reduction in IOP in a rat glaucoma model without adverse effects.
Hosseini et al.
Exp.Eye Res., 2006;82:753
Topical WIN55212-2 alleviates intraocular hypertenision in rats through a CB1 receptor mediated mechanism of action.
Oltmanns et al.
The citations listed below are publications that use Tocris products. Selected citations for Tocrisolve™ 100 include:
15 Citations: Showing 1 - 10