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Tocrisolve™ 100

Catalog #: 1684
25 Citations Datasheet / COA / SDS

Discontinued Product

1684 has been discontinued.
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Tocrisolve™ 100 | Additional Cannabinoid-related Compounds
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Description: Water-soluble emulsion; negative control for reagents in TocrisolveTM 100
Product Details
Citations (25)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Water soluble emulsion composed of a 1:4 ratio of soya oil/water that is emulsified with the block co-polymer Pluronic F68. Can be diluted with any aqueous medium. Used to solubilize hydrophobic organic chemicals and water-insoluble lipids such as cannabinoids and vanilloids. The cannabinoid or vanilloid is incorporated with the emulsion as part of a specialized innovative production process. The soya oil forms a coating around the cannabinoid molecule, and the block co-polymer is added to stabilize the emulsion, preventing the lipid droplets from coalescing (merging) in the surrounding water. Also can be used as a negative control for reagents in TocrisolveTM 100; Anandamide, AM 404, VDM 11, ACPA, (R)-(+)-Methanandamide, JWH 133 and Arachidonic acid (Cat. Nos. 1017, 1685, 1686, 1781, 1782, 1783 and 2756 respectively).

Technical Data

Storage:
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:

Product Datasheets

Reconstitution Calculator

Reconstitution Calculator

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Citations for Tocrisolve™ 100

The citations listed below are publications that use Tocris products. Selected citations for Tocrisolve™ 100 include:

25 Citations: Showing 1 - 10

  1. Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors.
    Authors: Diniz Et al.
    PeerJ  2019;7:e6493
  2. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis.
    Authors: Medina-Rodríguez Et al.
    Sci Rep  2017;7:43545
  3. Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.
    Authors: Chen Et al.
    Sci Rep  2016;6:33307
  4. Enhanced Production of Adenosine Triphosphate by Pharmacological Activation of Adenosine Monophosphate-Activated Protein Kinase Ameliorates Acetaminophen-Induced Liver Injury.
    Authors: Hwang Et al.
    J Neuroinflammation  2015;38:843
  5. Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra.
    Authors: Nishikawa Et al.
    Br J Pharmacol  2015;10:e0135701
  6. Anti-inflammatory effects of cannabinoid CB(2) receptor activation in endotoxin-induced uveitis.
    Authors: Toguri Et al.
    Behav Brain Res  2014;171:1448
  7. Cannabinoid receptor type-2 stimulation, blockade, and deletion alters the vascular inflammatory responses to traumatic brain injury.
    Authors: Amenta Et al.
    PLoS One  2014;11:191
  8. Inhibition of p38/Mk2 signaling pathway improves the anti-inflammatory effect of WIN55 on mouse experimental colitis.
    Authors: Li Et al.
    Lab Invest  2013;93:322
  9. Rapid Glucocorticoid-Induced Activation of TRP and CB1 Receptors Causes Biphasic Modulation of Glutamate Release in Gastric-Related Hypothalamic Preautonomic Neurons.
    Authors: Boychuk Et al.
    Front Neurosci  2013;7:3
  10. Electroacupuncture modulation of reflex hypertension in rats: role of cholecystokinin octapeptide.
    Authors: Li Et al.
    Am J Physiol Regul Integr Comp Physiol  2013;305:R404
  11. Treatment with CB2 agonist JWH-133 reduces histological features associated with erectile dysfunction in hypercholesterolemic mice.
    Authors: Fraga-Silva Et al.
    Clin Dev Immunol  2013;2013:263846
  12. Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice.
    Authors: Redondo Et al.
    ACS Chem Neurosci  2012;3:793
  13. The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques.
    Authors: Montecucco Et al.
    Br J Pharmacol  2012;33:846
  14. Inhibition of GSK3 attenuates amphetamine-induced hyperactivity and sensitization in the mouse.
    Authors: Enman and Unterwald
    J Neurosci  2012;231:217
  15. Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.
    Authors: Hilgers Et al.
    J Pharmacol Exp Ther  2010;333:210
  16. Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization.
    Authors: Zhang Et al.
    Eur J Neurosci  2010;31:225
  17. Selective reduction of cholecystokinin-positive basket cell innervation in a model of temporal lobe epilepsy.
    Authors: Wyeth Et al.
    J Neurosci  2010;30:8993
  18. Allosteric block of KCa2 channels by apamin.
    Authors: Lamy Et al.
    J Biol Chem  2010;285:27067
  19. Endocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex.
    Authors: Ho Et al.
    Br J Pharmacol  2010;160:736
  20. Effect of the CB(1) receptor antagonists rimon. and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices.
    Authors: Mendiguren and Pineda
    Br J Pharmacol  2009;158:1579
  21. Differential endocannabinoid regulation of baroreflex-evoked sympathoinhibition in normotensive versus hypertensive rats.
    Authors: Brozoski Et al.
    Auton Neurosci  2009;150:82
  22. Processing cardiovascular information in the vlPAG during electroacupuncture in rats: roles of endocannabinoids and GABA.
    Authors: Tjen-A-Looi Et al.
    J Appl Physiol (1985)  2009;106:1793
  23. Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons.
    Authors: Akerman Et al.
    J Pharmacol Exp Ther  2007;320:64
  24. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression.
    Authors: Esposito Et al.
    Br J Pharmacol  2007;151:1272
  25. Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats.
    Authors: Gaskari Et al.
    Eur Heart J  2005;146:315

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