Chemical Name: 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
Biological ActivityPotent and selective inhibitor of PI 3-kinase γ (IC50 values are 33 and 935 nM for PI 3-Kγ and PI 3-Kα respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Sequential activation of class IB and IA PI3K is important for the primed respiratory burst of human but not murine neutrophils.
Condliffe et al.
Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ.
Pomel et al.
Citation for AS 252424
The citations listed below are publications that use Tocris products. Selected citations for AS 252424 include:
1 Citation: Showing 1 - 1
Identification and characterization of a novel class of c-Jun N-terminal kinase inhibitors.
Authors: Schepetkin Et al.
Mol Pharmacol 2012;81:832
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