ATP disodium salt

Catalog # Availability Size / Price Qty
ATP disodium salt | CAS No. 987-65-5 | P2Y Receptor Agonists
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Description: P2 agonist

Chemical Name: Adenosine 5'-triphosphate disodium salt

Purity: ≥99%

Product Details
Citations (3)
Supplemental Products
Reviews (5)

Biological Activity

ATP disodium salt is a P2 purinoceptor agonist.

Technical Data

Soluble to 100 mM in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Extracellular ATP: effects, sources and fate.
    Biochem.J, 1986;233:309
  2. Dependence of P2-nucleotide receptor agonist-mediated endothelium-indepdent relaxation on ectonucleotidase acticity and A2A-receptors in rat portal vein.
    Guilbert et al.
    Br.J.Pharm., 1998;123:1732
  3. Historical review: ATP as a neurotransmitter.
    Burnstock and Kenned
    Trends Pharm.Sci., 2006;27:16

Product Datasheets

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Citations for ATP disodium salt

The citations listed below are publications that use Tocris products. Selected citations for ATP disodium salt include:

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Reviews for ATP disodium salt

Average Rating: 5 (Based on 5 Reviews)

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great to use for the synthesis of complexes and for its use in biological assays
By Anonymous on 07/02/2019
Application: Species: Human

I used it to prepare a complex at 1mM concentration.

Kinase Assay ATP Kinetics
By Brian Englar on 02/06/2019
Application: Species: Human

Used this ATP for kinase assays with IRAK4 and a TAK1 inhibitor to determine Km and Vmax. Worked well with no issues and can freeze thaw with no issues.

Great for kinase assays and kinetics
By Scott Scarneo on 02/06/2019
Application: Species: Human

I used this product for a kinase assay to look at enzyme kinetics. Worked great and was pure with no issues on solubility or contamination.

Exreacellular ATP stimulates IL-1b production in macrophages
By Chintan Koyani on 10/23/2018
Application: Species: Mouse

RAW macrophages were incubated with ATP (5 mM) for 4 h to follow IL-1b mRNA expression using qPCR. ATP treatment induced inflammatory signalling in macrophages most likely via P2 receptor.

P2 agonist
By Anonymous on 05/17/2018
Application: Species: Mouse

ATP, as expected, activates multiple P2 receptor responses, in cell culture and in brain slices.

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