ATP disodium salt

Tocris Bioscience | Catalog # 3245

P2 agonist
Tocris Bioscience

Key Product Details

Description

P2 agonist
View all P2Y Receptor Agonists »

Product Description

ATP disodium salt is a P2 purinoceptor agonist.

Product Specifications for ATP disodium salt

Molecular Weight

551.14

Formula

C10H14N5Na2O13P3

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

Adenosine 5'-triphosphate disodium salt

CAS Number

987-65-5

PubChem ID

13803

InChI Key

TTWYZDPBDWHJOR-IDIVVRGQSA-L

SMILES

O[C@@H]1[C@@H](COP(OP(OP(O)([O-])=O)([O-])=O)(O)=O)O[C@@H](N3C2=NC=NC(N)=C2N=C3)[C@@H]1O.[Na+].[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 55.11 100

Preparing Stock Solutions for ATP disodium salt

The following data is based on the product molecular weight 551.14.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.81 mL 9.07 mL 18.14 mL
5 mM 0.36 mL 1.81 mL 3.63 mL
10 mM 0.18 mL 0.91 mL 1.81 mL
50 mM 0.04 mL 0.18 mL 0.36 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 20 publications citing the usage of this product.

  • Guilbert Dependence of P2-nucleotide receptor agonist-mediated endothelium-indepdent relaxation on ectonucleotidase acticity and A2A-receptors in rat portal vein. Br.J.Pharm.
  • Burnstock and Kenned Historical review: ATP as a neurotransmitter. Trends Pharm.Sci.
  • Gordon Extracellular ATP: effects, sources and fate. Biochem.J 1986 PMID: 3006665

Product Documents for ATP disodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ATP disodium salt

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for ATP disodium salt

Customer Reviews for ATP disodium salt (5)

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  • great to use for the synthesis of complexes and for its use in biological assays
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 07/02/2019
    The product is highly soluble in water thus the most suitable solvent for it to use.
    I used it to prepare a complex at 1mM concentration.
  • Kinase Assay ATP Kinetics
    Name: Brian Englar
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 02/06/2019
    Used this ATP for kinase assays with IRAK4 and a TAK1 inhibitor to determine Km and Vmax. Worked well with no issues and can freeze thaw with no issues.
    ATP disodium salt 3245
  • Great for kinase assays and kinetics
    Name: Scott Scarneo
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 02/06/2019
    I used this product for a kinase assay to look at enzyme kinetics. Worked great and was pure with no issues on solubility or contamination.
    ATP disodium salt 3245
  • Exreacellular ATP stimulates IL-1b production in macrophages
    Name: Chintan Koyani
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Macrophages
    Verified Customer | Posted 10/23/2018
    RAW macrophages were incubated with ATP (5 mM) for 4 h to follow IL-1b mRNA expression using qPCR. ATP treatment induced inflammatory signalling in macrophages most likely via P2 receptor.
    ATP disodium salt 3245
  • P2 agonist
    Name: Anonymous
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 05/17/2018
    ATP, as expected, activates multiple P2 receptor responses, in cell culture and in brain slices.

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