BAIAP2 Antibody

Name: BAIAP2 Antibody
Brand: Novus Biologicals
SKU: NB100-827
Price: 399 USD
Availability: InStock

Novus Biologicals | Catalog # NB100-827

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

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Product Specifications

Immunogen

Peptide with sequence C-SGSGTLVSTV corresponding to C-Terminus according to NP_059344.1.

Specificity

This antibody is expected to recognise only human isoform 1 according to NP_059344.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for BAIAP2 Antibody

Western Blot: BAIAP2 Antibody [NB100-827]

Western Blot: BAIAP2 Antibody [NB100-827] - Staining of Human Brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NB100-827]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NB100-827] - Staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for BAIAP2 Antibody

Application

Recommended Usage

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Peptide ELISA

Detection limit 1:64000

Western Blot

1 - 3 ug/ml

Application Notes

WB: Approx. 60 kDa band observed in human brain lysates (calculated MW of 57.4 kDa band according to NP_059344.1). IHC: Paraffin embedded Human Brain (Cortex).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BAIAP2

BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This antibody is expected to recognise the human isoform 1 only of this protein.

Alternate Names

BAI1-associated protein 2IRS-58, BAI-associated protein 2, BAP2, brain-specific angiogenesis inhibitor 1-associated protein 2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, IRSP53, IRSp53/58, Protein BAP2

Entrez Gene IDs

10458 (Human); 108100 (Mouse); 117542 (Rat)

Gene Symbol

BAIAP2

UniProt

NP_059344. (Human)

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Product Documents for BAIAP2 Antibody

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Product Specific Notices for BAIAP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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