BAIAP2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-88711

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence, Simple Western

Cited:

Western Blot, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all BAIAP2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: WFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNP

Reactivity Notes

Use in Mouse reported in scientific literature (PMID:31483294).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BAIAP2 Antibody - BSA Free

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebellum, cerebral cortex, fallopian tube and prostate using Anti-BAIAP2 antibody NBP1-88711 (A) shows similar protein distribution across tissues to independent antibody (B).
Western Blot: BAIAP2 Antibody [NBP1-88711]

Western Blot: BAIAP2 Antibody [NBP1-88711]

Western Blot: BAIAP2 Antibody [NBP1-88711] - Analysis in rat cell line NBT-II.
Immunocytochemistry/ Immunofluorescence: BAIAP2 Antibody [NBP1-88711]

Immunocytochemistry/ Immunofluorescence: BAIAP2 Antibody [NBP1-88711]

Immunocytochemistry/Immunofluorescence: BAIAP2 Antibody [NBP1-88711] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol. Antibody staining is shown in green.
Western Blot: BAIAP2 Antibody [NBP1-88711]

Western Blot: BAIAP2 Antibody [NBP1-88711]

Western Blot: BAIAP2 Antibody [NBP1-88711] - Analysis in human cell line A-431.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human fallopian tube shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human prostate shows moderate to strong cytoplasmic and membranous positivity in glandular cells.

Applications for BAIAP2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Simple Western

1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BAIAP2

BAIAP2 is encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the 3'-end of this gene results in three products of undetermined function.

Alternate Names

BAI1-associated protein 2IRS-58, BAI-associated protein 2, BAP2, brain-specific angiogenesis inhibitor 1-associated protein 2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, IRSP53, IRSp53/58, Protein BAP2

Gene Symbol

BAIAP2

Additional BAIAP2 Products

Product Documents for BAIAP2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for BAIAP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for BAIAP2 Antibody - BSA Free

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Protocols

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FAQs

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