Potent selective estrogen receptor modulator (SERM) (IC50
values are 26 and 99 nM for ERα
respectively). Inhibits 17β
-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene
(Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from Pfizer Inc.
Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity.
Komm et al.