TMEM16A/B calcium-activated chloride channel (CaCC) blocker. Inhibits ATP-induced mucin secretion and metacholine-induced airway smooth muscle contraction in vitro
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Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.
Gallos et al.
Am.J.Physiol.Lung Cell Mol.Physiol., 2013;305:625
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.
Huang et al.