beta-2 Adrenergic R/ADRB2 Antibody (4C11) - BSA Free

Novus Biologicals | Catalog # NBP3-26521

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4C11 expressed in HEK293

Format

BSA Free
View all beta-2 Adrenergic R/ADRB2 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human beta-2 Adrenergic R/ADRB2 [UniProt P07550]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta-2 Adrenergic R/ADRB2 Antibody (4C11) - BSA Free

beta-2 Adrenergic R/ADRB2 Antibody (4C11)

Immunohistochemistry: beta-2 Adrenergic R/ADRB2 Antibody (4C11) [NBP3-26521] -

Immunohistochemistry: beta-2 Adrenergic R/ADRB2 Antibody (4C11) [NBP3-26521] - Image of beta-2 Adrenergic R/ADRB2 Antibody (4C11) diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
beta-2 Adrenergic R/ADRB2 Antibody (4C11)

Immunohistochemistry: beta-2 Adrenergic R/ADRB2 Antibody (4C11) [NBP3-26521] -

Immunohistochemistry: beta-2 Adrenergic R/ADRB2 Antibody (4C11) [NBP3-26521] - Image of beta-2 Adrenergic R/ADRB2 Antibody (4C11) diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Applications for beta-2 Adrenergic R/ADRB2 Antibody (4C11) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, and 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: beta-2 Adrenergic R/ADRB2

The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues. Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver. The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity. Agonists of ADRB2 are most widely used for the treatment of asthma. In complex with beta-arrestin-1 and c-src, the beta-2 adrenergic receptor activates MAP kinases ERK1(MAPK3) and ERK2 (MAPK1). Expression of the beta-2 adrenoceptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. ESTs have been isolated from breast, liver, liver/spleen, placenta, and uterus libraries.

Long Name

Beta-2 Adrenergic Receptor

Alternate Names

ADRB2, ADRB2R, B2AR, beta-2 AdrenergicR, beta2 AdrenergicR

Gene Symbol

ADRB2

Additional beta-2 Adrenergic R/ADRB2 Products

Product Documents for beta-2 Adrenergic R/ADRB2 Antibody (4C11) - BSA Free

Certificate of Analysis

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Product Specific Notices for beta-2 Adrenergic R/ADRB2 Antibody (4C11) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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