185 results for "beta-2 Adrenergic R/ADRB2" in Products

beta-2 Adrenergic R/ADRB2 Products

ADRB2 is a member of the G protein-coupled receptor superfamily that is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. ADRB2 binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by ADRB2. Different polymorphic forms, point mutations, and/or downregulation of ADRB2 are associated with nocturnal asthma, obesity and type 2 diabetes.

Standard selective β agonist

Alternate Names: Isoprenaline
Chemical Name: 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride
Purity: ≥98%
Isoproterenol affects the rate of cardiomyocyte contraction
(2)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat, Zebrafish
Details: Rabbit IgG Monoclonal Clone #JM102-06
Applications: IHC, WB, ICC/IF, IP
Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody (JM102-06) [NBP2-67187]
(6)
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Highly selective β2 inverse agonist

Chemical Name: (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride
Purity: ≥98%
Highly selective β2 inverse agonist
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β antagonist

Chemical Name: (RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
(2)
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Recombinant Monoclonal Antibody.

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2204C
Applications: WB
Detection of Human, Mouse, and Rat  beta -2 Adrenergic R/ADRB2 antibody by Western Blot.
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Long-acting β2 agonist; bronchodilator

Chemical Name: 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthalenecarboxylic acid salt
Purity: ≥98%
Long-acting β2 agonist; bronchodilator
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α1, β1 and β2 agonist

Chemical Name: 4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride
Purity: ≥98%
α1, β1 and β2 agonist
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Reactivity: Human, Rat
Details: Mouse IgG1 Monoclonal Clone #5G3B5
Applications: WB, ELISA, Flow
Western Blot: beta-2 Adrenergic R/ADRB2 Antibody (5G3B5)BSA Free [NBP2-61710]
(5)
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β2-adrenoceptor agonist

Alternate Names: Albuterol
Chemical Name: α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol hemisulfate
Purity: ≥98%
β2-adrenoceptor agonist
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5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist

Chemical Name: 4-[3-[tert-Butylamino]-2-hydroxypropoxy]-1H-indole-2-carbonitrile hemifumarate
Purity: ≥98%
5-HT1A and 5-HT1B antagonist; also β-adrenergic antagonist
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β3 partial agonist. β1/β2 antagonist

Chemical Name: 4-[3-[(1,1-Dimethylethyl)amino]2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one hydrochloride
β3 partial agonist. β1/β2 antagonist
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Potent and non-selective β antagonist; also potent α1 antagonist

Alternate Names: BM 14190
Chemical Name: 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
Purity: ≥98%
Potent and non-selective β antagonist; also potent α1 antagonist
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Potent β2 agonist

Chemical Name: (±)-erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]carbostyril hydrochloride
Purity: ≥98%
Potent β2 agonist
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #586107
Applications: Flow, CyTOF-ready
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: beta-2 Adrenergic R/ADRB2 Antibody [NBP1-90227]
(4)
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Potent and selective β2 agonist

Alternate Names: BD 40A
Chemical Name: (±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide hemifumarate
Purity: ≥98%
Potent and selective β2 agonist
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Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Alternate Names: Org 3770,6-Azamianserin
Chemical Name: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Purity: ≥98%
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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Long-acting β2 agonist (LABA)

Chemical Name: N-[2-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide L-tartrate
Purity: ≥98%
Long-acting β2 agonist (LABA)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #4A6C9
Applications: WB, ELISA, Flow
Western Blot: beta-2 Adrenergic R/ADRB2 Antibody (4A6C9)BSA Free [NBP2-61711]
(4)
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Reactivity: Human
Applications:
R&D Systems VersaClone cDNA Plasmids
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Reactivity: Human
Applications:
R&D Systems VersaClone cDNA Plasmids
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Recombinant Monoclonal Antibody

Reactivity: Human
Details: Rabbit IgG Kappa Monoclonal Clone #R11/E1
Applications: WB, Flow, ICC/IF, IP
Immunocytochemistry/ Immunofluorescence: beta-2 Adrenergic R/ADRB2 Antibody (R11/E1) - Chimeric - Azide and BSA Free [NBP3-12006]
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #586107
Applications: Flow
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Recombinant Monoclonal Antibody.

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #2204C
Applications: WB
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