Catalog Number: 0109
Chemical Name: [R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide
Biological Activity
Methobromide salt of (+)-bicuculline. Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

Methoiodide Salt and Methochloride Salt also available.

Technical Data
  • M.Wt:
    462.3
  • Formula:
    C21H20BrNO6
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    73604-30-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Recent advances in the pharmacology of quaternary salts of bicuculline.
    Seutin and Johnson
    TiPS, 1999;20:268
  2. Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes.
    Bowery et al.
    Br.J.Pharmacol., 1983;78:191
  3. Nigral infusions of muscimol or bicuculline facilitate seizures in developing rats.
    Sperber et al.
    Brain Res., 1987;465:243
Citations:

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