Human GABA-A R alpha 1 (NP_000797) VersaClone cDNA

Catalog # Availability Size / Price Qty
R&D Systems VersaClone cDNA Plasmids
1 Image
Product Details
Supplemental Products

Human GABA-A R alpha 1 (NP_000797) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Product Datasheets

You must select a language.


Background: GABA-A R alpha 1

GABA A (γ-aminobutyric acid-type A) receptors are members of the cysteine-loop family of neurotransmitter-gated ion channels. GABA binding to A-type receptors induces anion-selective ion channel opening. These receptors are the principal fast inhibitory neurotransmitter receptors in the CNS. GABA A receptors are heteropentamer combinations of seven subunit types; α, β, γ, δ, ε, θ, and π. Three subunits, α, β, and γ, have at least three separate gene products in mammals, and typical GABA A receptors have some combination of α, β, and γ subunits.

The rat α1 isoform is a 50 - 52 kDa, 428 amino acid (aa), 4 transmembrane protein with two terminal extracellular regions. The ligand-binding region is in the N-terminus (aa 15 - 222). As with many receptors, phosphorylation of GABA A R is used as a regulatory mechanism. CaM kinase II is known to phosphorylate the a1 GABA A subunit and regulate benzodiazepine binding. The α1 subunits are particularly abundant in the cerebellum and may contribute to GABA receptor distribution. In the hippocampus and amygdala, the α1 GABA A subunit may contribute to amnesia.

Long Name
gamma-Aminobutyric Acid Type A Receptor, alpha-1 Polypeptide
Entrez Gene IDs
2554 (Human); 14394 (Mouse); 29705 (Rat); 282235 (Bovine)
Alternate Names
ECA4; EJM; EJM5GABA(A) receptor subunit alpha-1; GABA A R alpha 1; GABAAR alpha 1; GABAARa1; GABRA1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; gamma-aminobutyric acid receptor subunit alpha-1


No product specific FAQs exist for this product, however you may

View all cDNA Clone FAQs

Reviews for Human GABA-A R alpha 1 (NP_000797) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human GABA-A R alpha 1 (NP_000797) VersaClone cDNA and earn rewards!

Have you used Human GABA-A R alpha 1 (NP_000797) VersaClone cDNA?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review