Human GABA-A R theta (AAF70380) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human GABA-A R theta (AAF70380) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: GABA-A R theta

The gamma-aminobutyric acid (GABAA) receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The GABAA receptors are a major site of action of a number of clinically important drugs. GABAQ is the theta subunit of the GABAA receptor. GABAQ has a unique distribution, with studies so far suggesting significant expression within monoaminergic neurons of both human and monkey brain. Expression of alpha2beta1gamma1theta in transfected mammalian cells leads to the formation of receptors with a 4-fold decrease in the affinity for gamma-aminobutyric acid compared with alpha2beta1gamma1.

Long Name
gamma-Aminobutyric Acid Type A Receptor, pi Polypeptide
Entrez Gene IDs
55879 (Human)
Alternate Names
GABA A R theta; GABA(A) receptor subunit theta; GABA-A receptor theta subunit; GABAAR theta; GABAARt; GABRQ; gamma-aminobutyric acid (GABA) receptor, theta; gamma-aminobutyric acid receptor subunit theta; MGC129629; MGC129630; THETA


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