Boc-VPR-AMC Fluorogenic Peptide Substrate

Substrate for Coagulation Factor II, Coagulation Factor VII, Kallikrein 4, Kallikrein 5, Kallikrein 8, Kallikrein 13, Kallikrein 14, and MASP3
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R&D Systems Fluorogenic Peptide Substrates
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Citations (15)
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Boc-VPR-AMC Fluorogenic Peptide Substrate Summary

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Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.


Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Citations for Boc-VPR-AMC Fluorogenic Peptide Substrate

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

15 Citations: Showing 1 - 10
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  1. Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits
    Authors: S Smiljanic, C Messaraa, V Lafon-Kolb, N Hrapovic, N Amini, C Osterlund, L Visdal-Joh
    International Journal of Molecular Sciences, 2022-10-19;23(20):.
    Species: Betula alba, Plant - Empetrum nigrum
    Sample Types: Complex Sample Type
    Applications: Bioassay
  2. WDR72 regulates vesicle trafficking in ameloblasts
    Authors: K Katsura, Y Nakano, Y Zhang, R Shemirani, W Li, P Den Besten
    Scientific Reports, 2022-02-18;12(1):2820.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  3. Chlorogenic Acid Isomers Isolated from Artemisia lavandulaefolia Exhibit Anti-Rosacea Effects In Vitro
    Authors: KB Roh, Y Jang, E Cho, D Park, DH Kweon, E Jung
    Biomedicines, 2022-02-16;10(2):.
    Species: Human
    Sample Types: Peptides
    Applications: Bioassay
  4. A Genus-Wide Bioactivity Analysis of Daboia (Viperinae: Viperidae) Viper Venoms Reveals Widespread Variation in Haemotoxic Properties
    Authors: B Op den Bro, FCP Coimbra, NR Casewell, SA Ali, FJ Vonk, BG Fry
    International Journal of Molecular Sciences, 2021-12-15;22(24):.
    Species: Snake
    Sample Types: Venom
    Applications: Bioassay
  5. Interleukin-1&beta-induced matrix metalloproteinase-3 via ERK1/2 pathway to promote mesenchymal stem cell migration
    Authors: CH Chang, YL Lin, YS Tyan, YH Chiu, YH Liang, CP Chen, JC Wu, HS Wang
    PLoS ONE, 2021-05-21;16(5):e0252163.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  6. Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix
    Authors: T Kryza, C Parent, J Pardessus, A Petit, J Burlaud-Ga, P Reverdiau, S Iochmann, V Labas, Y Courty, N Heuzé-Vour
    Sci Rep, 2018-04-20;8(1):6331.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Enzyme Assay
  7. Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus)
    Authors: J Debono, J Dobson, NR Casewell, A Romilio, B Li, N Kurniawan, K Mardon, V Weisbecker, A Nouwens, HF Kwok, BG Fry
    Toxins (Basel), 2017-05-19;9(5):.
    Species: Snake
    Sample Types: Venom
    Applications: Enzyme Assay Substrate
  8. Protease-inhibitor interaction predictions: Lessons on the complexity of protein-protein interactions
    Authors: N Fortelny, GS Butler, CM Overall, P Pavlidis
    Mol. Cell Proteomics, 2017-04-06;0(0):.
    Applications: Bioassay
  9. Free Fatty Acids Modulate Thrombin Mediated Fibrin Generation Resulting in Less Stable Clots
    PLoS ONE, 2016-12-12;11(12):e0167806.
    Species: Human
    Sample Types: Protein
  10. Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway.
    Authors: Kryza T, Achard C, Parent C, Marchand-Adam S, Guillon-Munos A, Iochmann S, Korkmaz B, Respaud R, Courty Y, Heuze-Vourc'h N
    FASEB J, 2013-11-13;28(2):740-51.
    Applications: Enzyme Assay
  11. RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner.
    Authors: Luis-Ravelo D, Anton I, Zandueta C, Valencia K, Pajares M, Agorreta J, Montuenga L, Vicent S, Wistuba I, De Las Rivas J, Lecanda F
    Mol Oncol, 2013-11-12;8(2):196-206.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Targeting tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in mice.
    Authors: Fernando S, Fletcher BS
    Cancer Res., 2009-06-15;69(12):5126-32.
  13. Activation profiles and regulatory cascades of the human kallikrein-related peptidases.
    Authors: Yoon H, Laxmikanthan G, Lee J, Blaber SI, Rodriguez A, Kogot JM, Scarisbrick IA, Blaber M
    J. Biol. Chem., 2007-09-06;282(44):31852-64.
    Species: Human
    Sample Types: Recombinant Protein
  14. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12).
    Authors: Memari</LastName><ForeNam N</Initial, Memari N, Jiang W, Diamandis EP, Luo LY
    Biol. Chem., 2007-04-01;388(4):427-35.
    Species: Human
    Sample Types: Recombinant Protein
  15. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5.
    Authors: Cortesio CL, Jiang W
    Arch. Biochem. Biophys., 2006-03-03;449(1):164-70.
    Species: Human
    Sample Types: Recombinant Protein


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Boc-VPR-AMC Fluorogenic Peptide Substrate
By Anonymous on 04/02/2020
Application: Enzymatic activity in vitro