Chemical Name: 1-(4-Chlorophenyl)-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride
Biological Activity Potently active primary amine metabolite of sibutramine (Cat. No. 2290), exhibits a similar pharmacological profile to the parent compound. Inhibits serotonin and noradrenalin reuptake more potently than sibutramine in vitro. Reduces food intake in rodents following i.c.v. administration and increases energy expenditure via thermogenesis in vivo.
Soluble to 50 mM in water and to 100 mM in DMSO
Desiccate at RT
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