BTS 54-505 hydrochloride

Discontinued Product

2322 has been discontinued.
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BTS 54-505 hydrochloride | CAS No. 84484-78-6 | 5-HT Transporter Inhibitors
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Description: Potent 5-HT and NA reuptake inhibitor (SNRI); active metabolite of sibutramine (Cat. No. 2290)

Chemical Name: 1-(4-Chlorophenyl)-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride

Purity: ≥99%

Product Details

Biological Activity

BTS 54-505 hydrochloride is a potently active primary amine metabolite of sibutramine (Cat. No. 2290), exhibits a similar pharmacological profile to the parent compound. Inhibits serotonin and noradrenalin reuptake more potently than sibutramine in vitro. Reduces food intake in rodents following i.c.v. administration and increases energy expenditure via thermogenesis in vivo.

Technical Data

Soluble to 50 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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