Cabergoline

  ( 2 citations )    
Product Datasheet
Catalog Number:2664
Chemical Name:N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)ergoline-8-carboxamide
Product Details
Citations (2)
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Biological Activity
Selective D2-like dopamine receptor agonist (Ki values are 0.7, 1.5, 9.0 and 165 nM for D2, D3, D4 and D5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (Ki = 1.2 - 20.0 nM for 5-HT1A, 5-HT1D, 5-HT2A and 5-HT2B). Inhibits secretion of prolactin and growth hormone and reverses levodopa-induced dyskinesias in Parkinsonian monkeys.
Technical Data
  • M.Wt:
    451.6
  • Formula:
    C26H37N5O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    81409-90-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Cabergoline include:

2 Citations: Showing 1 - 2
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  1. Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline.
    Authors: Lin Et al.
    PLoS One  2015;6:39329
  2. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity.
    Authors: Odaka Et al.
    J Biol Chem  2014;9:e99271

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