Cancer Immunotherapy: Tumor Microenvironment

Graphic of the tumor microenvironment

A large body of evidence suggests that tumors create an immunosuppressive microenvironment that inhibits the immune system’s natural ability to recognize and destroy tumor cells. This is accomplished via several mechanisms, including the recruitment of immunosuppressive cells, activation of immune checkpoint pathways, and exclusion of T cells. Gaining a better understanding of these immunosuppressive mechanisms will provide an important step towards developing novel strategies to overcome this obstacle to cancer immunotherapies. Trust the products and services offered by R&D Systems, your leading provider of immunology reagents, to investigate the immunosuppressive tumor microenvironment. Click the links below to learn more and find the products you are looking for.

Immunotherapy Homepage


Immunosuppressive Cells

We offer the products you need to investigate the tumor promoting effects of immunosuppressive cells in the tumor microenvironment.

Immune Checkpoint Pathways

Blockade of immune checkpoint pathways is a promising therapeutic approach for cancer treatment. Browse our wide range of products for immune checkpoint blockade research.

T Cell Exclusion

Find products to investigate T cell exclusion mechanisms and learn about potential therapeutic strategies to counteract these mechanisms.

Custom Solutions

Expedite your research by partnering with our industry-renowned product development scientists to acquire unique reagents that fit your exact needs.