Cannabinoid R2/CB2/CNR2 Antibody

Novus Biologicals | Catalog # NB300-606

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Cannabinoid R2/CB2/CNR2 Primary Antibodies »

Product Specifications

Immunogen

A fusion protein containing the first 33 amino acid residues from human CB2.

Specificity

Cannabinoid Receptor 2

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cannabinoid R2/CB2/CNR2 Antibody

Western Blot: Cannabinoid R2/CB2/CNR2 Antibody [NB300-606]

Western Blot: Cannabinoid R2/CB2/CNR2 Antibody [NB300-606]

Western Blot: Cannabinoid R2/CB2/CNR2 Antibody [NB300-606] - Analysis of 25 ug of PC-3 (lane 1) and Jurkat (lane 2) cell lysates.

Applications for Cannabinoid R2/CB2/CNR2 Antibody

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunohistochemistry-Frozen

1:100

Immunohistochemistry-Paraffin

1:100

Western Blot

1:250 - 1:2500
Application Notes
WB: Detects an approx. 60 kDa protein representing CB2 from human spinal cord homogenate.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA and 30% glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cannabinoid R2/CB2/CNR2

Cannabinoids exert their well known physiological effects through two G protein coupled receptors, cannabinoid receptor 1 (CB1) and CB2. Both cannabinoid receptors have been shown to inhibit adenylyl cyclase as well as stimulate the mitogen-activated protein kinase, MAPK. CB1 receptors also modulate ion channels through direct G-protein interactions. Delta 9-tetrahydrocannibinol and related ligands likely exert their psychoactive effects by inhibiting presynaptic N- and P / Q type calcium channels. CB2 is thought to function primarily in the immune system although it has been suggested to be present in the central nervous system, including the retina.

Long Name

Cannabinoid Receptor 2

Alternate Names

CannabinoidR2, CB2R, CNR2, CX5

Entrez Gene IDs

1269 (Human)

Gene Symbol

CNR2

Additional Cannabinoid R2/CB2/CNR2 Products

Product Documents for Cannabinoid R2/CB2/CNR2 Antibody

Certificate of Analysis

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Product Specific Notices for Cannabinoid R2/CB2/CNR2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Cannabinoid R2/CB2/CNR2 Antibody

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Protocols

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