CCR5 Antibody

Novus Biologicals | Catalog # NB100-714

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rhesus Macaque, Virus

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CCR5 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide 3YQVSSPIYDINYYTSEPCQKINVKQIAA30 corresponding to the N-terminal sequence of human CCR5

Reactivity Notes

Virus reactivity reported in scientific literature (PMID: 25067937).

Localization

Plasma membrane

Specificity

This binds to CCR 5 receptors on human peripheral blood leukocytes as determined by immunohistochemistry.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CCR5 Antibody

Immunohistochemistry-Paraffin: CCR5 Antibody [NB100-714]

Immunohistochemistry-Paraffin: CCR5 Antibody [NB100-714]

Immunohistochemistry-Paraffin: CCR5 Antibody [NB100-714] - Paraffin sections of human spleen tissue.

Applications for CCR5 Antibody

Application
Recommended Usage

ELISA

1:25000

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

10mM KHPO4 and 0.14M NaCl, BSA @ 1mg/ml

Preservative

0.1% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CCR5

Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co-receptor. The chemokine receptor CCR 5 is one of the co-receptors used by primary isolates of HIV-1. Extracellular domains of CCR 5 are important for HIV entry into the target cells.

Alternate Names

CCR5, CD195

Entrez Gene IDs

1234 (Human)

Gene Symbol

CCR5

Additional CCR5 Products

Product Documents for CCR5 Antibody

Certificate of Analysis

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Product Specific Notices for CCR5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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