CD11c Antibody - BSA Free

Name: CD11c Antibody - BSA Free
Brand: Novus Biologicals
SKU: NBP1-91210
Price: 519 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-91210

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRV

Marker

Dendritic Cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CD11c Antibody - BSA Free (NBP1-91210) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CD11c Antibody - BSA Free

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210]

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210] - Staining of human testis shows strong membranous and cytoplasmic positivity in spermatids.

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210]

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210] - Staining of human lung shows weak membranous and cytoplasmic positivity in macrophages.

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210]

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210] - Staining of human skeletal muscle shows no membranous positivity in myocytes as expected.

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210]

Immunohistochemistry-Paraffin: CD11c Antibody [NBP1-91210] - Staining of human tonsil shows moderate membranous positivity in germinal center cells.

Immunohistochemistry: CD11c Antibody - BSA Free [NBP1-91210]

Analysis in human spleen and skeletal muscle tissues using NBP1-91210 antibody. Corresponding ITGAX RNA-seq data are presented for the same tissues.

Immunohistochemistry: CD11c Antibody - BSA Free [NBP1-91210]

Staining of human spleen shows strong membranous positivity in cells in white pulp.

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Applications for CD11c Antibody - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD11c

CD11c encodes the integrin alpha X chain protein. CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

Alternate Names

CD11c, Integrin alpha X, ITGAX, p150,95 alpha

Gene Symbol

ITGAX

Additional CD11c Products

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Product Specific Notices for CD11c Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.